Hy-Vee Acquires 22 Shopko Pharmacies in 17 Cities Including Watertown

WEST DES MOINES, Iowa (Dec. 14, 2018) — Hy-Vee, Inc. announced today that it has acquired the business of 22 Shopko pharmacies in Iowa, Illinois, Minnesota, Nebraska, South Dakota and Wisconsin. Shopko patient files will merge into existing Hy-Vee Pharmacy locations in the 17 cities where the acquisitions have taken place.  Files from the Watertown Shopko Store will merge with the Watertown Hy-Vee store pharmacy.

“As we continue to grow our pharmacy business, we pride ourselves on providing an excellent experience to our customers,” said Randy Edeker, Hy-Vee’s chairman of the board, CEO and president. “We provide customized care for each person who walks through our door. Our pharmacists will go above and beyond to provide numerous services to our patients so we can help them understand and assist with caring for their specific health care needs.”

In addition to traditional pharmacy services, Hy-Vee Pharmacy locations feature free prescription delivery, automated refill ordering, immunization services, free blood pressure checks, private medication consultations and a registered dietitian available for nutritional consultations. Generic prescriptions are available for $4 for a 30-day supply or $10 for a 90-day supply.

Hy-Vee pharmacies are also integrated into the free Hy-Vee mobile app for both iOS and Android devices for easy prescription management.

All impacted Shopko pharmacy patients will receive a letter from their new Hy-Vee Pharmacy with additional details.

Each person who fills a new prescription or refills an existing/transferred prescription at any Hy-Vee Pharmacy location will receive a 5 cents per gallon Fuel Saver + Perks discount, which can be redeemed at any Hy-Vee location that sells gasoline, and a coupon for a discount on his/her next Hy-Vee grocery trip.

The dates when specific Hy-Vee pharmacies will begin filling these prescriptions in each city are listed below.

Date

Hy-Vee Location

Dec. 18, 2018

Watertown Hy-Vee

1320 9th Ave., S.E.

Watertown, South Dakota

Dec. 18, 2018

Whitney Way Hy-Vee

675 S. Whitney Way

Madison, Wisconsin

Hy-Vee, Inc. • 5820 Westown Parkway • West Des Moines, Iowa • 50266

Dec. 19, 2018

Hilltop Hy-Vee

2010 Adams St.

Mankato, Minnesota

Dec. 19, 2018

Hy-Vee on South Minnesota

3000 S. Minnesota Ave.

Sioux Falls, South Dakota

Dec. 19, 2018

Sycamore Avenue Hy-Vee

1601 S. Sycamore Ave.

Sioux Falls, South Dakota

Dec. 20, 2018

Marshall Hy-Vee

900 E. Main St.

Marshall, Minnesota

Dec. 20, 2018

Crossroads Hy-Vee

500 Crossroads Drive, S.W.

Rochester, Minnesota

Dec. 20, 2018

Fairmont Hy-Vee

907 S. State St.

Fairmont, Minnesota

Jan. 4, 2019

Winona Hy-Vee

1475 W. Service Drive

Winona, Minnesota

Jan. 4, 2019

Albert Lea Hy-Vee

2708 Bridge Ave.

Albert Lea, Minnesota

Jan. 8, 2019

37th Street Hy-Vee

500 37th St., N.W.

Rochester, Minnesota

Jan. 8, 2019

Grand Island Hy-Vee

115 Wilmar Ave.

Grand Island, Nebraska

Jan. 8, 2019

Stony Brook Hy-Vee

14591 Stony Brook Blvd.

Omaha, Nebraska

Jan. 9, 2019

O Street Hy-Vee

5010 O St.

Lincoln, Nebraska

Jan. 9, 2019

Austin Hy-Vee

1307 18th Ave., N.W.

Austin, Minnesota

Jan. 9, 2019

Hy-Vee West

2107 Taylor Ave.

Norfolk, Nebraska

Jan. 10, 2019

Hy-Vee on Broadway

3700 Broadway St.

Quincy, Illinois

Jan. 10, 2019 Williamsburg Hy-Vee 6001 Village Drive Lincoln, Nebraska

Jan. 23, 2019 Mason City Hy-Vee Drugstore 875 Fourth St., S.W.

Mason City, Iowa

Jan. 23, 2019 Hy-Vee on Hamilton 2827 Hamilton Blvd. Sioux City, Iowa

Jan. 23, 2019 Glenwood Hy-Vee Clinic Pharmacy 409 S. Locust Glenwood, Iowa

SDSU researcher targeting drug-resistant cancer cells

BROOKINGS, S.D. - Dec. 14, 2018 - A South Dakota State University researcher is finding new ways to destroy cancer cells that develop resistance to multiple chemotherapy drugs.

“Chemotherapy is the most common treatment for cancers,” explained Assistant Professor Surtaj Iram of the Department of Chemistry and Biochemistry. “However, one of the biggest obstacles to success is cancer cells that acquire resistance to multiple drugs.” As a result, the cancer cells stop responding to these therapeutic drugs.

Through a one-year, nearly $90,000 grant from the South Dakota Board of Regents, Iram will use a new imaging technique to discover drugs that can disrupt one of the main mechanisms through which cancer cells gain resistance—over expression of multidrug resistance protein 1, known as MRP1. In addition, he seeks to discover novel drugs that can selectively kill MRP1-over expressing multidrug resistant cancer cells.

“Our long-term goal is to overcome multidrug resistance in cancer and to improve the effectiveness and reduce the toxicity of chemotherapy drugs,” explained Iram, who has been at South Dakota State for four years. He is one of the researchers working with South Dakota’s BioSystems Networks and Translational Research Center.

Iram has been doing cancer research for nearly 13 years, first as a postdoctoral researcher at Columbia University, then at the Queen’s University Cancer Research Institute in Canada and most recently at the Loyola University Stritch School of Medicine in Chicago. He earned his doctoral degree in biochemistry from the University of Illinois, Urbana-Champaign, in 2005.

“Although cancer cells use different mechanisms to become multidrug resistant, over expression of MRP1 is a frequently used mechanism in many types of cancer,” Iram said.

MRP1 is a protein on the cell surface that serves as a gatekeeper, he explained. “Any drug needs to go past these gatekeepers.” MRP1 protects the cell by pumping out harmful molecules to prevent toxin buildup. Other researchers have shown that mice that do not produce this protein are hypersensitive to toxic drugs.

However, over expression of MRP1 causes the protein to pump out the chemotherapy drugs, thereby protecting cancer cells and making them resistant to multiple therapeutic drugs. MRP1, for instance, plays a role in neuroblastoma, a rare childhood cancer that affects the nervous system.

“This protein has both a positive and negative role,” Iram explained. “We want to shut off the route through which MRP1 clears therapeutic drugs from the cell, but keep the doors open for the positive job this protein is doing.”

Using a newly developed fluorescent imaging technique, Iram and his team of graduate and undergraduate students will screen 386 anticancer compounds that are now in clinical trials and 1,443 compounds that have recently received FDA approval.

In addition, the researchers will use two lines of cells, one that is sensitive to and one that is resistant to chemotherapy drugs, to identify whether any of these compounds might be able to kill multidrug resistant cancer cells.

“Collateral sensitivity is the idea behind the discovery of drugs that can selectively kill MRP1-overexpressing multidrug resistant cancer cells,” Iram explained. “Gaining strength in one area usually creates weakness in another area—everything in nature comes at a price.” For instance, MRP1 plays a role in regulating glutathione levels. Glutathione is the most abundant antioxidant in the body. If there is less glutathione due to MRP1-overexpression, the cell may be more prone to oxidative damage.

“We will take these drugs that are already in the pipeline and find a new role for them,” Iram said. That will then create an opportunity for a licensing agreement with the company that is developing the drug.

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